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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FLT4 All Species: 25.45
Human Site: Y833 Identified Species: 56
UniProt: P35916 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35916 NP_002011.2 1298 145599 Y833 E Q C E Y L S Y D A S Q W E F
Chimpanzee Pan troglodytes XP_518160 1359 151684 Y833 E Q C E Y L S Y D A S Q W E F
Rhesus Macaque Macaca mulatta XP_001107118 1294 145144 G780 P R E R L H L G R V L G Y G A
Dog Lupus familis XP_538585 1362 152583 Y833 E Q C E Y L S Y D A S Q W E F
Cat Felis silvestris
Mouse Mus musculus P35917 1363 152998 Y833 E Q C E Y L S Y D A S Q W E F
Rat Rattus norvegicus Q91ZT1 1363 153298 Y833 E Q C E Y L S Y D V S Q W E F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517468 812 91764 K380 F I N V E W R K G P L I E A T
Chicken Gallus gallus Q8QHL3 1327 149408 Y807 E Q C E C L P Y D A S K W E I
Frog Xenopus laevis Q91909 954 106841 G522 I G F I A A A G L M C I A V A
Zebra Danio Brachydanio rerio Q5MD89 1357 153159 Y854 E Q C E Y L P Y D S S Q W E I
Tiger Blowfish Takifugu rubipres P79750 975 110895 K543 V F L L Y K Y K Q K P R F E I
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.5 91.7 85 N.A. 84.4 84.3 N.A. 42.5 41.3 25.9 52 27.1 N.A. N.A. N.A. N.A.
Protein Similarity: 100 91.6 92.9 88.9 N.A. 88.6 88.1 N.A. 50.4 58.7 42.9 67.4 43.2 N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 0 100 N.A. 100 93.3 N.A. 0 73.3 0 80 13.3 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 13.3 100 N.A. 100 93.3 N.A. 0 80 6.6 86.6 26.6 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 10 10 0 0 46 0 0 10 10 19 % A
% Cys: 0 0 64 0 10 0 0 0 0 0 10 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 64 0 0 0 0 0 0 % D
% Glu: 64 0 10 64 10 0 0 0 0 0 0 0 10 73 0 % E
% Phe: 10 10 10 0 0 0 0 0 0 0 0 0 10 0 46 % F
% Gly: 0 10 0 0 0 0 0 19 10 0 0 10 0 10 0 % G
% His: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 10 0 10 0 0 0 0 0 0 0 19 0 0 28 % I
% Lys: 0 0 0 0 0 10 0 19 0 10 0 10 0 0 0 % K
% Leu: 0 0 10 10 10 64 10 0 10 0 19 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % M
% Asn: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 10 0 0 0 0 0 19 0 0 10 10 0 0 0 0 % P
% Gln: 0 64 0 0 0 0 0 0 10 0 0 55 0 0 0 % Q
% Arg: 0 10 0 10 0 0 10 0 10 0 0 10 0 0 0 % R
% Ser: 0 0 0 0 0 0 46 0 0 10 64 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % T
% Val: 10 0 0 10 0 0 0 0 0 19 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 10 0 0 0 0 0 0 64 0 0 % W
% Tyr: 0 0 0 0 64 0 10 64 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _